Charly - here are a couple of ‘out there’ situations I’ve seen with Transponders. I’m not a ‘licensed‘ tech however i find that helps as I wasn’t trained to think in one direction
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1st - composite aircraft, Txpdr would drop out sometimes & the range was reduced ( on a route that the customer travelled frequently).
A shop pulled the unit & bench tested (all good), then replaced the RG58 coax to antenna with RG 400 (good idea) however drop out symptoms were the same. He contacted me ( Glasair owner as well) & I offered to look at it. After accessing antenna I found the ‘problem’ within 10 seconds ( he had spent approx $1500 up until this point).
This was the answer - looking directly into the antenna BNC (socket) fitting there is a brass like tube, that is a smaller diameter than the pin on the cable, has splits in it making 4 segments so that when the cable is attached the pin from the BNC fitting spreads them slightly & are tight against the pin.
2 of those segments were missing, go figure. Replaced antenna, problem solved.
2nd - similar issue with another aircraft in CTA - Txpdr was dropping out, Licensed Techs ( I was the Service Manager) supposedly checked everything including KT76 A, replaced antenna cable & bench tested - all good. Aircraft went flying & returned due Txpdr ‘failure’. On further investigation I found they’d only replaced the main cable from the 1ft pigtail at the rack end ( a lot of the early Kings, Narco etc,etc had a short cable ( pigtail) at the Txpdr end to assist in troubleshooting. When that old RG58 pigtail was removed the ‘fault’ was obvious - the shield from that cable is soldered to the 90* fitting & with age etc everyone of the shield strands were broken resulting in the reported Txpdr fault. What was happening was sometimes a single or more wire strands would & then would not make contact due cable movement due temperature or vibration. ‘Pigtail’ cable replaced = problem solved.
HTH, sorry to be so long winded.