Dynon replied the inflight cal is NOT necessary.
update ——-
Went and redid just the ground calibration. On the runway for takeoff and landing at that airport and my home airport the heading was within 1 to 2° of charted runway heading. (Previously 10° off after in flight cal)
Winds aloft were still a little wonky, but very light winds so I will have to test again. So far it looks like ground calibration works fine, and in-flight calibration messes the whole thing up. Will update Dynon and the message board.