We don't often deal with the GTN 625, and the references I found online were ambiguous as to whether the GTN 625 provides an ARINC-429 interface, or not, or whether it's an option.
IF the GTN 625 (or, if an option, your unit has one installed), AND you have (or will install) a Dynon Avionics HS34 HSI Control Panel (provides an ARINC-429 interface for the FlightDEK-D180), the AP coupling to the FlightDEK-D180 is generally better than connecting via serial. For example, the AP data to the FlightDEK-D180's AP includes turn anticipation - those "sentences" aren't transmitted over serial - only transmitted on ARINC-429.
I have D-180 which I use for Altitude hold and GPS feed from G-496. Now I'm updating to Garmin GTN-625 and wander how much the D-180 can benefit from it, and wiring info.
Have been looking for hours at the installation manual, but no joy? Hope someone has more experience on the matter.
Thanks.