There are obviously differing methods, including mine -
note : the aluminium ‘casting’ of the pitot base, that fits into the mount, has 4 x ‘pads’ that are much thicker than the rest of the oval area - that’s the area that you drill & tap threads through, in a later step.
All below can be done before the tube mount is fitted for the last time.
Eyeball & mark a point (I use a fine point permanent marker) that is at 90deg to the outside of the curved surface, & does not interfere with the tubes when drilling, mark a line vertical down the pitot body (& onto the mount when the pitot is fitted to the mount) need also to allow for a horizontal point after the mount & tube are together for drilling Initially use a 3/32” drill for drilling through the assembled mount & pitot tube. Separate both & drill/ tap as necessary.
Drill the mount to allow for short 6-32 screw.
Drill & tap the TUBE, using a bit sized for 6-32 screw, carefully & use something like Boeshield during the process - you’ll need to do this progressively, by inserting/extracting the tap, cleaning out the swerve & using the boeshield again because of the soft alloy which can be easily stripped out. HTH.
It’s much easier to do this process with the mount & tube off the plane - that’s why I nearly 100% always mount the pitot tube on an inspection panel YMMV
